Scientists at the State University of Novosibirsk participated in the construction of the first 3D model of Zika virus, according to the press office of the institution. The development is part of the "Zooparl of the virus."
"The prototype was created based on scientific data for structural bioinformatics methods and has atomic detail. The virus construction model could help scientists to develop diagnostics and vaccines fever awakened by the tropical virus," it reads in document released by the university.
Researchers at the State University of Novosibirsk built models of individual proteins - the capsule of a virus is generally dormada by a glycoprotein membrane - in addition to analyzing the scientific data on the root of the virus to understand how the different components of Zika virus They have the virion (infectious viral particles).
The analysis of the protein of the capsule and Zika virus (which, in the model was checked with different shades of blue) showed that it resembles the corresponding protein of the dengue virus.
"The experiments really show that antibody against the Zika virus is related to the dengue virus and vice versa. This makes the task of diagnosing it is more complicated", reads the document.
It was precisely the mutation of this protein capsule that allowed the creation in 1937 of yellow fever vaccine. In addition, the researchers say they have reason to believe that particular properties of the protein capsule and causes microcephaly in children whose mothers fall ill during pregnancy.
"If 'contaminate' this protein there inserting a mutation that let the virus survive, so can we get a good vaccine," reads the text.
The project non-commercial "Zoopark of the virus," the Russian company Visual Science, has created three-dimensional prototype immunodeficiency virus, H1N1, Ebola, papilloma and adenoviruses.
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