"Our experience shows a new relationship between the brain and the gut," said Josef Anrather, one of the authors of the research, in a statement from Cornell University. "[The study] will impact the way the medical community views and define the risk of stroke," he explains.
The research results were found after scientists induce an ischemic stroke - when a clogged blood vessel prevents blood from reaching the brain - in two groups of rats. The first, which was treated with antibiotics had 60% less damage than the second group, which received no medication.
According to scientists, the intestinal microbial environment influenced the immune cells to follow to the meninges, the outer covering of the brain, where they have organized to reduce the impact of stroke. Thus, the stroke did not hit the mice with full force.
"One of the most surprising findings was that the immune system did minor spills to orchestrate the outside of the brain response, as a teacher who does not play an instrument itself, but instructs the other, creating the music itself," said Costantino Iadecola , one of the authors of the study.
The phase of clinical trials in humans has not yet time to start. If this relationship between bacteria and the brains of people hold true, the study can help create targeted treatments to protect patients at high risk of suffering a stroke or increase protection of individuals against brain damage from new diets.
"Diets are easier to follow than the use of drugs," said Anrather. "The diet has the greatest effect on the composition of the microbial environment and as beneficial species are identified, we can approach them with a dietary intervention," he concludes.
Nenhum comentário:
Postar um comentário